Clinical Significance
Under the Microscope
Bacterial Vaginosis (BV):
Up to 95% of women having BV harbor Gardnerella vaginalis (GV)
GV is also found in up to 50% of women with asymptomatic BV
Up to 75% of women with BV are asymptomatic
Mobiluncus spp. are rare in asymptomatic BV and is so is a more sensitive marker.
Advantages of MDx
Approximately 30 percent of patients with initial responses to therapy have a recurrence of symptoms within three months.
Improper diagnosis will lead to inappropriate treatment and can result in the recurrence of the disease.
Vaginitis Screening
Vaginitis Screening
0 Differentiation of 5 pathogens
G. vaginalis
C. albicans
T. vaginalis
Mobiluncus spp
C. glabrata
Bacterial Vaginosis
0 Identification of 6 bacteria
A. vaginae
G. vaginalis
M. mulieris
B. fragilis
M. curtisii
P. bivia
Vaginitis is the most commonly encountered female ailment in gynecology, affecting up to 29% of the female population at any time. Vaginitis accounts for more than 19 million doctor visits each year
Vaginitis can be separated into three main categories:
Bacterial Vaginosis (BV)
Polymicrobial infectionCandidiasis (CV)
Recurrent and non-recurrentTrichomoniasis (TV)
The most common & curable STD
Up to 25% of vaginitis cases are caused by mixed infections
Candida Vaginitis (CV):
Candida albicans is the most frequently found cause of CV that are non-complicated and non-recurrent!
Up to 50% of women with CV have complicated and recurrent episodes.
Candida glabrata causes up to 20% of CV, most of which are complicated and recurring.
Bacterial VaginosisCandida Vaginitis
0 Detection of 6 Candida species
C. albicans
C. glabrata
C. parapsilosis
C. dubliniensis
C. krusei
C. tropicalis